Impact of combiner aerobic and resistance training on depression: a systematic review and meta-analysis of randomized controlled trials

Abstract Objective To summarize the existing literature and evaluate the efficacy of combined resistance and aerobic training in alleviating depressive symptoms among individuals with depression. Subgroup analyses were conducted based on study region, age, depression severity, intervention duration,...

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Main Authors: Hai Wang, Qinzheng Liu, Yingxu Pan
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Sports Science, Medicine and Rehabilitation
Subjects:
Online Access:https://doi.org/10.1186/s13102-025-01058-w
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author Hai Wang
Qinzheng Liu
Yingxu Pan
author_facet Hai Wang
Qinzheng Liu
Yingxu Pan
author_sort Hai Wang
collection DOAJ
description Abstract Objective To summarize the existing literature and evaluate the efficacy of combined resistance and aerobic training in alleviating depressive symptoms among individuals with depression. Subgroup analyses were conducted based on study region, age, depression severity, intervention duration, intervention frequency, and whether the intervention was supervised or unsupervised. Methods Five databases were thoroughly examined from database establishment until August 20, 2024, to find randomized controlled trials that investigated resistance combined aerobic training impact on depression. Results Finally, 27 eligible studies were included, involving a total of 2,342 patients with depression. The outcomes indicated that resistance combined aerobic training notably improved signs of depression in these patients (SMD=-1.39, 95%CI=-1.80 to -0.96, p = 0.000). Subgroup analysis based on study area, age, severity of depressive symptoms, and exercise prescription revealed that resistance combined aerobic training had a particularly significant effect on middle-aged and elderly patients with depression, as well as on those with moderate depression. Additionally, moderate period (9–24 weeks), moderate frequency (3–4 times per week), a total weekly duration of more than 180 min and supervised training displayed the best results. Conclusion Resistance combined aerobic training serves as an efficient approach to relieve depression-related symptoms, particularly in middle-aged and elderly patients with depression and those with moderate depression. Moderate training intensity, duration, frequency, and total weekly duration offer the greatest benefit.
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spelling doaj-art-a6917701b0614a9f8388d54337cce8982025-01-26T12:47:18ZengBMCBMC Sports Science, Medicine and Rehabilitation2052-18472025-01-0117112110.1186/s13102-025-01058-wImpact of combiner aerobic and resistance training on depression: a systematic review and meta-analysis of randomized controlled trialsHai Wang0Qinzheng Liu1Yingxu Pan2Capital University of Physical Education and SportsCapital University of Physical Education and SportsCapital University of Physical Education and SportsAbstract Objective To summarize the existing literature and evaluate the efficacy of combined resistance and aerobic training in alleviating depressive symptoms among individuals with depression. Subgroup analyses were conducted based on study region, age, depression severity, intervention duration, intervention frequency, and whether the intervention was supervised or unsupervised. Methods Five databases were thoroughly examined from database establishment until August 20, 2024, to find randomized controlled trials that investigated resistance combined aerobic training impact on depression. Results Finally, 27 eligible studies were included, involving a total of 2,342 patients with depression. The outcomes indicated that resistance combined aerobic training notably improved signs of depression in these patients (SMD=-1.39, 95%CI=-1.80 to -0.96, p = 0.000). Subgroup analysis based on study area, age, severity of depressive symptoms, and exercise prescription revealed that resistance combined aerobic training had a particularly significant effect on middle-aged and elderly patients with depression, as well as on those with moderate depression. Additionally, moderate period (9–24 weeks), moderate frequency (3–4 times per week), a total weekly duration of more than 180 min and supervised training displayed the best results. Conclusion Resistance combined aerobic training serves as an efficient approach to relieve depression-related symptoms, particularly in middle-aged and elderly patients with depression and those with moderate depression. Moderate training intensity, duration, frequency, and total weekly duration offer the greatest benefit.https://doi.org/10.1186/s13102-025-01058-wResistance training, Depression, Aerobic training, Meta-analysis
spellingShingle Hai Wang
Qinzheng Liu
Yingxu Pan
Impact of combiner aerobic and resistance training on depression: a systematic review and meta-analysis of randomized controlled trials
BMC Sports Science, Medicine and Rehabilitation
Resistance training, Depression, Aerobic training, Meta-analysis
title Impact of combiner aerobic and resistance training on depression: a systematic review and meta-analysis of randomized controlled trials
title_full Impact of combiner aerobic and resistance training on depression: a systematic review and meta-analysis of randomized controlled trials
title_fullStr Impact of combiner aerobic and resistance training on depression: a systematic review and meta-analysis of randomized controlled trials
title_full_unstemmed Impact of combiner aerobic and resistance training on depression: a systematic review and meta-analysis of randomized controlled trials
title_short Impact of combiner aerobic and resistance training on depression: a systematic review and meta-analysis of randomized controlled trials
title_sort impact of combiner aerobic and resistance training on depression a systematic review and meta analysis of randomized controlled trials
topic Resistance training, Depression, Aerobic training, Meta-analysis
url https://doi.org/10.1186/s13102-025-01058-w
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