Establishment of salivary tissue-organoid biorepository: characterizing salivary gland stem/progenitor cells and novel differentiation marker PSMA/FOLH1

Establishment of salivary tissue-organoid biorepository: characterizing salivary gland stem/progenitor cells and novel differentiation marker PSMA/FOLH1

Abstract The salivary gland (SG) is vital for oral function and overall health through secretion of saliva. However salivary dysfunction due to aging, medications, autoimmune disorders, and cancer treatments poses significant challenges. We established the first diverse and clinically annotated sali...

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Main Authors: Syed Mohammed Musheer Aalam, Ana Rita Varela, Aalim Khaderi, Ronsard J. Mondesir, Dong-Gi Mun, Andrew Ding, Isabelle M. A. Lombaert, Rob P. Coppes, Chitra Priya Emperumal, Akhilesh Pandey, Jeffrey R. Janus, Nagarajan Kannan
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-025-00410-5
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https://doi.org/10.1038/s41536-025-00410-5

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