Overexpressed Wnt-7a acts as a potential antitumor immune modulator and predicts poor prognosis in HNSCC

Overexpressed Wnt-7a acts as a potential antitumor immune modulator and predicts poor prognosis in HNSCC

Immune checkpoint inhibitor (ICI) has become the first-line treatment of advanced head and neck squamous cell carcinoma (HNSCC), which has a relatively poor clinical prognosis and high mortality. However, only a proportion of patients respond well to ICI therapy. Identifying reliable predictive mark...

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Bibliographic Details
Main Authors: Hui-chao Jiang, Ya Gao, Shu-yan Wang, Yong-lan Zhao, Hai-peng Sun
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Heliyon
Subjects:
Wnt-7a
Antitumor immunity
Tumor immune microenvironment
Immune check point inhibitor
HNSCC
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025011752
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