Age-specific familial risks in cancer as clues to germline genetic and environmental causes: focus on colorectal, endometrial, prostate, kidney, breast and lung cancers

Age-specific familial risks in cancer as clues to germline genetic and environmental causes: focus on colorectal, endometrial, prostate, kidney, breast and lung cancers

Abstract Background The Swedish Family-Cancer Database (FCD) is the largest source of data on familial cancer in the world, including practically complete family structures and individual cancer diagnoses from the high-quality cancer registry. We present a novel application of FCD by analyzing age-s...

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Bibliographic Details
Main Authors: Kari Hemminki, Asta Försti, Otto Hemminki, Rodney J. Scott, Akseli Hemminki
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Familial risk
Germline genetics
Heredity
Age of onset
Early onset
Online Access:https://doi.org/10.1186/s13053-024-00301-8
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https://doi.org/10.1186/s13053-024-00301-8

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