Mechanisms of natural killer cell-mediated clearance of senescent renal tubular epithelial cells

IntroductionIntact kidney function is essential for fluid and electrolyte homeostasis, with renal tubular epithelial cells providing critical functions in the reabsorption or secretion of numerous metabolites. Cellular senescence of the renal epithelial cells can lead to functional deficits. Therefo...

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Bibliographic Details
Main Authors: Nils David Funk, Julius Sinning, Patrick Schaser, Inga Soerensen-Zender, Vera Christine Wulfmeyer, Kai Schmidt-Ott, Korbinian Brand, Stephan Halle, Roland Schmitt
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1597230/full
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