Synergistic activity of Pitstop-2 and 1,6-hexanediol in aggressive human lung cancer cells

Abstract Metastatic cancer cells undergo metabolic reprogramming, which involves changes in the metabolic fluxes, including endocytosis, nucleocytoplasmic transport, and mitochondrial metabolism, to satisfy their massive demands for energy, cell division, and proliferation compared to normal cells....

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Bibliographic Details
Main Authors: Sílvio Terra Stefanello, Caren Rigon Mizdal, Aline Franzen da Silva, Luca Matteo Todesca, Félix Alexandre Antunes Soares, Victor Shahin
Format: Article
Language:English
Published: Springer 2025-01-01
Series:Discover Nano
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Online Access:https://doi.org/10.1186/s11671-025-04184-z
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