Human papillomavirus vaccination hesitancy among young girls in Ethiopia: factors and barriers to uptake
BackgroundHuman papillomavirus (HPV) vaccinations protect against HPV infections. The infection might lead to vaginal cancer, vulvar cancer, genital warts, cervical intraepithelial neoplasia lesions, and cervical cancer. This study assessed hesitancy of HPV vaccination, associated factors, and barri...
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Frontiers Media S.A.
2025-01-01
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| author | Ashenafi Kibret Sendekie Ashenafi Kibret Sendekie Biruk Beletew Abate Biruk Beletew Abate Betelhem Anteneh Adamu Aschalew Mulatu Tefera Kaleab Temelket Mekonnen Melkam Alemu Ashagrie Yabibal Berie Tadesse Abera Dessie Dagnaw Mequannent Sharew Melaku Gizachew Kassahun Bizuneh |
| author_facet | Ashenafi Kibret Sendekie Ashenafi Kibret Sendekie Biruk Beletew Abate Biruk Beletew Abate Betelhem Anteneh Adamu Aschalew Mulatu Tefera Kaleab Temelket Mekonnen Melkam Alemu Ashagrie Yabibal Berie Tadesse Abera Dessie Dagnaw Mequannent Sharew Melaku Gizachew Kassahun Bizuneh |
| author_sort | Ashenafi Kibret Sendekie |
| collection | DOAJ |
| description | BackgroundHuman papillomavirus (HPV) vaccinations protect against HPV infections. The infection might lead to vaginal cancer, vulvar cancer, genital warts, cervical intraepithelial neoplasia lesions, and cervical cancer. This study assessed hesitancy of HPV vaccination, associated factors, and barriers to vaccination among youth girls in Ethiopia.MethodsAn institutional-based cross-sectional study was conducted among female undergraduate students at the University of Gondar, College of Medicine and Health Sciences, between July and August 2022. The data was collected using a self-administered questionnaire. A simple random sampling method was used to recruit participants. The data were entered and analyzed with SPSS version 26. Descriptive statistics were used to describe the participants’ demographic characteristics. Logistic regression was performed to identify the significant factors associated with acceptance of the HPV vaccine. A p-value <0.05 was considered statistically significant.ResultsThe study included 423 participants with a mean age of 22.5 ± 6.7 years. Only more than one-third (35.2, 95% CI: 27.2–44.1) received the HPV vaccine. Currently, more than one-fourth (27.9, 95% Cl: 21.4–33.8) of participants are hesitant to receive the HPV vaccine. Higher monthly income (AOR = 1.52, 95% CI: 1.08–6.34), good knowledge of the HPV vaccine (AOR = 2.12, 95% CI: 1.12–4.87), and a positive attitude towards the vaccine (AOR = 3.03, 95% CI: 1.63–9.56) were significantly associated with acceptance of HPV vaccination. Safety concerns (63.1%), misinformation (42.8%), and parental concerns (42.3%) about the HPV vaccine were among the top perceived reported barriers to receiving the HPV vaccine.ConclusionThis result showed that more than a quarter number of youth girls are still hesitant to receive HPV vaccinations. To increase vaccination acceptance, interventions should focus on awareness-raising programs about HPV infection and vaccines and addressing safety and parental concerns. |
| format | Article |
| id | doaj-art-a6023dd964b044a68f119a70c9c18e0e |
| institution | Kabale University |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
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| spelling | doaj-art-a6023dd964b044a68f119a70c9c18e0e2025-01-23T05:10:24ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-01-011310.3389/fpubh.2025.15078321507832Human papillomavirus vaccination hesitancy among young girls in Ethiopia: factors and barriers to uptakeAshenafi Kibret Sendekie0Ashenafi Kibret Sendekie1Biruk Beletew Abate2Biruk Beletew Abate3Betelhem Anteneh Adamu4Aschalew Mulatu Tefera5Kaleab Temelket Mekonnen6Melkam Alemu Ashagrie7Yabibal Berie Tadesse8Abera Dessie Dagnaw9Mequannent Sharew Melaku10Gizachew Kassahun Bizuneh11Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaSchool of Pharmacy, Curtin Medical School, Faculty of Health Sciences, Curtin University, Bentley, WA, AustraliaCollege of Medicine and Health Sciences, Woldia University, Woldia, EthiopiaSchool of Population Health, Curtin University, Bentley, WA, AustraliaDepartement of Pharmacognosy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaDepartement of Pharmacognosy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaDepartement of Pharmacognosy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaDepartement of Pharmacognosy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaDepartment of Pharmaceutical Chemistry, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaDepartment of Pharmaceutical Chemistry, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaDepartment of Health Informatics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaDepartement of Pharmacognosy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaBackgroundHuman papillomavirus (HPV) vaccinations protect against HPV infections. The infection might lead to vaginal cancer, vulvar cancer, genital warts, cervical intraepithelial neoplasia lesions, and cervical cancer. This study assessed hesitancy of HPV vaccination, associated factors, and barriers to vaccination among youth girls in Ethiopia.MethodsAn institutional-based cross-sectional study was conducted among female undergraduate students at the University of Gondar, College of Medicine and Health Sciences, between July and August 2022. The data was collected using a self-administered questionnaire. A simple random sampling method was used to recruit participants. The data were entered and analyzed with SPSS version 26. Descriptive statistics were used to describe the participants’ demographic characteristics. Logistic regression was performed to identify the significant factors associated with acceptance of the HPV vaccine. A p-value <0.05 was considered statistically significant.ResultsThe study included 423 participants with a mean age of 22.5 ± 6.7 years. Only more than one-third (35.2, 95% CI: 27.2–44.1) received the HPV vaccine. Currently, more than one-fourth (27.9, 95% Cl: 21.4–33.8) of participants are hesitant to receive the HPV vaccine. Higher monthly income (AOR = 1.52, 95% CI: 1.08–6.34), good knowledge of the HPV vaccine (AOR = 2.12, 95% CI: 1.12–4.87), and a positive attitude towards the vaccine (AOR = 3.03, 95% CI: 1.63–9.56) were significantly associated with acceptance of HPV vaccination. Safety concerns (63.1%), misinformation (42.8%), and parental concerns (42.3%) about the HPV vaccine were among the top perceived reported barriers to receiving the HPV vaccine.ConclusionThis result showed that more than a quarter number of youth girls are still hesitant to receive HPV vaccinations. To increase vaccination acceptance, interventions should focus on awareness-raising programs about HPV infection and vaccines and addressing safety and parental concerns.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1507832/fullHuman papillomavirusHPV vaccinevaccine hesitancyvaccination acceptanceknowledgeattitude |
| spellingShingle | Ashenafi Kibret Sendekie Ashenafi Kibret Sendekie Biruk Beletew Abate Biruk Beletew Abate Betelhem Anteneh Adamu Aschalew Mulatu Tefera Kaleab Temelket Mekonnen Melkam Alemu Ashagrie Yabibal Berie Tadesse Abera Dessie Dagnaw Mequannent Sharew Melaku Gizachew Kassahun Bizuneh Human papillomavirus vaccination hesitancy among young girls in Ethiopia: factors and barriers to uptake Frontiers in Public Health Human papillomavirus HPV vaccine vaccine hesitancy vaccination acceptance knowledge attitude |
| title | Human papillomavirus vaccination hesitancy among young girls in Ethiopia: factors and barriers to uptake |
| title_full | Human papillomavirus vaccination hesitancy among young girls in Ethiopia: factors and barriers to uptake |
| title_fullStr | Human papillomavirus vaccination hesitancy among young girls in Ethiopia: factors and barriers to uptake |
| title_full_unstemmed | Human papillomavirus vaccination hesitancy among young girls in Ethiopia: factors and barriers to uptake |
| title_short | Human papillomavirus vaccination hesitancy among young girls in Ethiopia: factors and barriers to uptake |
| title_sort | human papillomavirus vaccination hesitancy among young girls in ethiopia factors and barriers to uptake |
| topic | Human papillomavirus HPV vaccine vaccine hesitancy vaccination acceptance knowledge attitude |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1507832/full |
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