A method for selecting P antigen-negative red cell units for patients with paroxysmal cold hemoglobinuria
In the absence of specific antisera and molecular typing technique, selection of P antigen-negative red cell unit is a challenge. This article explains a new technique that can be used in emergency situations to screen P antigen-negative red cell unit for the transfusion of patients with paroxysmal...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-01-01
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| Series: | Asian Journal of Transfusion Science |
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| Online Access: | https://journals.lww.com/10.4103/ajts.AJTS_65_19 |
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| _version_ | 1832593736227356672 |
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| author | Geethika Sajeewani Manchanayake |
| author_facet | Geethika Sajeewani Manchanayake |
| author_sort | Geethika Sajeewani Manchanayake |
| collection | DOAJ |
| description | In the absence of specific antisera and molecular typing technique, selection of P antigen-negative red cell unit is a challenge. This article explains a new technique that can be used in emergency situations to screen P antigen-negative red cell unit for the transfusion of patients with paroxysmal cold hemoglobinuria tested positive for Donath-Landsteiner antibody. The technique is based on the theory behind the Donath-Landsteiner test, and it can be performed even in a transfusion laboratory with minimum facilities. |
| format | Article |
| id | doaj-art-a5f75cb663904fd4b7e1b9bb8dce4029 |
| institution | Kabale University |
| issn | 0973-6247 1998-3565 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Journal of Transfusion Science |
| spelling | doaj-art-a5f75cb663904fd4b7e1b9bb8dce40292025-01-20T09:41:01ZengWolters Kluwer Medknow PublicationsAsian Journal of Transfusion Science0973-62471998-35652024-01-0118114815010.4103/ajts.AJTS_65_19A method for selecting P antigen-negative red cell units for patients with paroxysmal cold hemoglobinuriaGeethika Sajeewani ManchanayakeIn the absence of specific antisera and molecular typing technique, selection of P antigen-negative red cell unit is a challenge. This article explains a new technique that can be used in emergency situations to screen P antigen-negative red cell unit for the transfusion of patients with paroxysmal cold hemoglobinuria tested positive for Donath-Landsteiner antibody. The technique is based on the theory behind the Donath-Landsteiner test, and it can be performed even in a transfusion laboratory with minimum facilities.https://journals.lww.com/10.4103/ajts.AJTS_65_19blood transfusionp antigen-negative bloodparoxysmal cold hemoglobinuria |
| spellingShingle | Geethika Sajeewani Manchanayake A method for selecting P antigen-negative red cell units for patients with paroxysmal cold hemoglobinuria Asian Journal of Transfusion Science blood transfusion p antigen-negative blood paroxysmal cold hemoglobinuria |
| title | A method for selecting P antigen-negative red cell units for patients with paroxysmal cold hemoglobinuria |
| title_full | A method for selecting P antigen-negative red cell units for patients with paroxysmal cold hemoglobinuria |
| title_fullStr | A method for selecting P antigen-negative red cell units for patients with paroxysmal cold hemoglobinuria |
| title_full_unstemmed | A method for selecting P antigen-negative red cell units for patients with paroxysmal cold hemoglobinuria |
| title_short | A method for selecting P antigen-negative red cell units for patients with paroxysmal cold hemoglobinuria |
| title_sort | method for selecting p antigen negative red cell units for patients with paroxysmal cold hemoglobinuria |
| topic | blood transfusion p antigen-negative blood paroxysmal cold hemoglobinuria |
| url | https://journals.lww.com/10.4103/ajts.AJTS_65_19 |
| work_keys_str_mv | AT geethikasajeewanimanchanayake amethodforselectingpantigennegativeredcellunitsforpatientswithparoxysmalcoldhemoglobinuria AT geethikasajeewanimanchanayake methodforselectingpantigennegativeredcellunitsforpatientswithparoxysmalcoldhemoglobinuria |