CytoBead ANA 2 assay - a novel method for the detection of antinuclear antibodies

CytoBead ANA 2 assay - a novel method for the detection of antinuclear antibodies

Abstract Detection of anti-nuclear autoantibodies (ANA) is based on a two-step algorithm including indirect immunofluorescence (IIF) on HEp2 cells and subsequent reflex/confirmatory testing for specific autoantibodies. Simultaneous cell- and microbead-based autoantibody detection by IIF may be utili...

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Main Authors: Tulchinsky Roei, Gilburd Boris, Shovman Yehuda, Tocut Milena, Zeruya Eleanor, Binyaminov Ariel, Davidson Tima, Thomas Büttner, Abdullah Nasser, Juliane Michel, Stefan Rödiger, Peter Schierack, Amital Howard, Dirk Roggenbuck, Shoenfeld Yehuda, Shovman Ora
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Anti-nuclear antibodies
Anti-DFS70 antibodies
Indirect immunofluorescence
Multiplexed assay
CytoBead technology
Online Access:https://doi.org/10.1038/s41598-025-04583-3
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https://doi.org/10.1038/s41598-025-04583-3

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