Allocating the Sample Size in Phase II and III Trials to Optimize Success Probability

<p>{\bf Background} Clinical trials of phase II and III often fail due to poor experimental planning. Here, the problem of allocating available resources, in terms of sample size, to phase II and phase III is studied with the aim of increasing success rate. The overall success probability (OSP...

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Bibliographic Details
Main Author: Daniele De Martini
Format: Article
Language:English
Published: Milano University Press 2014-11-01
Series:Epidemiology, Biostatistics and Public Health
Online Access:http://ebph.it/article/view/9958
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