Massive Fetomaternal Hemorrhage Caused by an Intraplacental Choriocarcinoma: A Case Report
Background. Intraplacental choriocarcinoma is a rare but highly malignant trophoblastic neoplasm. When found near term the risk of maternal metastasis is high because of the late diagnosis. Case. We describe a case of an intraplacental choriocarcinoma diagnosed postpartum after a near-term delivery...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2010/767218 |
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| author | Anna-Karina Aaris Henningsen Lisa Leth Maroun Hanne Havsteen Jens Svare |
| author_facet | Anna-Karina Aaris Henningsen Lisa Leth Maroun Hanne Havsteen Jens Svare |
| author_sort | Anna-Karina Aaris Henningsen |
| collection | DOAJ |
| description | Background. Intraplacental choriocarcinoma is a rare but highly malignant trophoblastic neoplasm. When found near term the risk of maternal metastasis is high because of the late diagnosis.
Case. We describe a case of an intraplacental choriocarcinoma diagnosed postpartum after a near-term delivery of a severely anemic infant. A fetomaternal hemorrhage resulted in a hemoglobin concentration in the infant of only 2,1 g/dL. Neither mother nor child showed signs of metastatic disease.
The macroscopic examination showed a hydropic placenta weighing more than 1 kilogram. Microscopy showed an intraplacental choriocarcinoma 3 cm in diameter. The tumor had infiltrated the maternal basal plate.
Conclusion. Fetomaternal bleeding is a rare form of presentation of choriocarcinoma but its presence should always warrant detailed examination of placenta, mother, and infant. |
| format | Article |
| id | doaj-art-a5d68edd32104c0982fcf13c5d8963e3 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-a5d68edd32104c0982fcf13c5d8963e32025-02-03T05:59:53ZengWileyCase Reports in Medicine1687-96271687-96352010-01-01201010.1155/2010/767218767218Massive Fetomaternal Hemorrhage Caused by an Intraplacental Choriocarcinoma: A Case ReportAnna-Karina Aaris Henningsen0Lisa Leth Maroun1Hanne Havsteen2Jens Svare3Department of Obstetrics and Gynecology, Glostrup Hospital, University of Copenhagen, Nodre Ringvej 37, 2600 Glostrup, DenmarkDepartment of Pathology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen, DenmarkDepartment of Oncology, Herlev Hospital, University of Copenhagen, Herlev Rinvej 75, 2730 Herlev, DenmarkDepartment of Obstetrics and Gynecology, Glostrup Hospital, University of Copenhagen, Nodre Ringvej 37, 2600 Glostrup, DenmarkBackground. Intraplacental choriocarcinoma is a rare but highly malignant trophoblastic neoplasm. When found near term the risk of maternal metastasis is high because of the late diagnosis. Case. We describe a case of an intraplacental choriocarcinoma diagnosed postpartum after a near-term delivery of a severely anemic infant. A fetomaternal hemorrhage resulted in a hemoglobin concentration in the infant of only 2,1 g/dL. Neither mother nor child showed signs of metastatic disease. The macroscopic examination showed a hydropic placenta weighing more than 1 kilogram. Microscopy showed an intraplacental choriocarcinoma 3 cm in diameter. The tumor had infiltrated the maternal basal plate. Conclusion. Fetomaternal bleeding is a rare form of presentation of choriocarcinoma but its presence should always warrant detailed examination of placenta, mother, and infant.http://dx.doi.org/10.1155/2010/767218 |
| spellingShingle | Anna-Karina Aaris Henningsen Lisa Leth Maroun Hanne Havsteen Jens Svare Massive Fetomaternal Hemorrhage Caused by an Intraplacental Choriocarcinoma: A Case Report Case Reports in Medicine |
| title | Massive Fetomaternal Hemorrhage Caused by an Intraplacental Choriocarcinoma: A Case Report |
| title_full | Massive Fetomaternal Hemorrhage Caused by an Intraplacental Choriocarcinoma: A Case Report |
| title_fullStr | Massive Fetomaternal Hemorrhage Caused by an Intraplacental Choriocarcinoma: A Case Report |
| title_full_unstemmed | Massive Fetomaternal Hemorrhage Caused by an Intraplacental Choriocarcinoma: A Case Report |
| title_short | Massive Fetomaternal Hemorrhage Caused by an Intraplacental Choriocarcinoma: A Case Report |
| title_sort | massive fetomaternal hemorrhage caused by an intraplacental choriocarcinoma a case report |
| url | http://dx.doi.org/10.1155/2010/767218 |
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