Evaluation of broad-spectrum protection by novel mRNA vaccines against SARS-CoV-2 variants (Delta, Omicron-BA.5, XBB-EG.5) in the golden hamster model

Abstract Background The SARS-CoV-2 virus has continuously evolved, with new variants like Delta, Omicron-BA.5, and XBB-EG.5 posing challenges to vaccine efficacy. mRNA vaccines have emerged as a promising tool due to their rapid development and adaptability. This study evaluates the protective effic...

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Bibliographic Details
Main Authors: Tong Yu, JunHong Xing, XinYu Zhuang, MingYao Tian
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-025-02787-7
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