Cardiovascular and Renal Links along the Cardiorenal Continuum

The cardiorenal syndrome includes the widely known relationship between kidney function and cardiovascular disease. A large number of patients have various degrees of heart and kidney dysfunction worldwide, both in developed and developing countries. Disorders affecting one of them mostly involve t...

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Main Authors: José A. García-Donaire, Luis M. Ruilope
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:International Journal of Nephrology
Online Access:http://dx.doi.org/10.4061/2011/975782
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author José A. García-Donaire
Luis M. Ruilope
author_facet José A. García-Donaire
Luis M. Ruilope
author_sort José A. García-Donaire
collection DOAJ
description The cardiorenal syndrome includes the widely known relationship between kidney function and cardiovascular disease. A large number of patients have various degrees of heart and kidney dysfunction worldwide, both in developed and developing countries. Disorders affecting one of them mostly involve the other. Such interactions represent the pathogenesis for a clinical condition called cardiorenal syndrome. Renal and cardiovascular disease shares similar etiologic risk factors. The majority of vascular events are caused by accelerated atherosclerosis. Moreover, cardiovascular events rarely occur in patients without underlying disease; rather, they typically take place as the final stage of a pathophysiological process that results in progressive vascular damage, including vital organ damage, specifically the kidney and the heart if these factors are uncontrolled. Chronic kidney disease is a novel risk factor included at this stage that accelerates both vascular and cardiac damage.
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series International Journal of Nephrology
spelling doaj-art-a5a9e46d0a2649739931e3bbc63bb95b2025-02-03T06:13:57ZengWileyInternational Journal of Nephrology2090-214X2090-21582011-01-01201110.4061/2011/975782975782Cardiovascular and Renal Links along the Cardiorenal ContinuumJosé A. García-Donaire0Luis M. Ruilope1Hypertension Unit, Hospital 12 de Octubre, Avenida Córdoba s/n, 28041 Madrid, SpainHypertension Unit, Hospital 12 de Octubre, Avenida Córdoba s/n, 28041 Madrid, SpainThe cardiorenal syndrome includes the widely known relationship between kidney function and cardiovascular disease. A large number of patients have various degrees of heart and kidney dysfunction worldwide, both in developed and developing countries. Disorders affecting one of them mostly involve the other. Such interactions represent the pathogenesis for a clinical condition called cardiorenal syndrome. Renal and cardiovascular disease shares similar etiologic risk factors. The majority of vascular events are caused by accelerated atherosclerosis. Moreover, cardiovascular events rarely occur in patients without underlying disease; rather, they typically take place as the final stage of a pathophysiological process that results in progressive vascular damage, including vital organ damage, specifically the kidney and the heart if these factors are uncontrolled. Chronic kidney disease is a novel risk factor included at this stage that accelerates both vascular and cardiac damage.http://dx.doi.org/10.4061/2011/975782
spellingShingle José A. García-Donaire
Luis M. Ruilope
Cardiovascular and Renal Links along the Cardiorenal Continuum
International Journal of Nephrology
title Cardiovascular and Renal Links along the Cardiorenal Continuum
title_full Cardiovascular and Renal Links along the Cardiorenal Continuum
title_fullStr Cardiovascular and Renal Links along the Cardiorenal Continuum
title_full_unstemmed Cardiovascular and Renal Links along the Cardiorenal Continuum
title_short Cardiovascular and Renal Links along the Cardiorenal Continuum
title_sort cardiovascular and renal links along the cardiorenal continuum
url http://dx.doi.org/10.4061/2011/975782
work_keys_str_mv AT joseagarciadonaire cardiovascularandrenallinksalongthecardiorenalcontinuum
AT luismruilope cardiovascularandrenallinksalongthecardiorenalcontinuum