Wound Healing and Omega-6 Fatty Acids: From Inflammation to Repair
Wound healing is an evolutionarily conserved process that is essential for species survival. Wound healing involves a series of biochemical and cellular events that are tightly controlled, divided into 3 concomitant and overlapping phases: inflammation, proliferation, and remodelling. Poor wound hea...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2018/2503950 |
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| author | Jéssica R. Silva Beatriz Burger Carolina M. C. Kühl Thamiris Candreva Mariah B. P. dos Anjos Hosana G. Rodrigues |
| author_facet | Jéssica R. Silva Beatriz Burger Carolina M. C. Kühl Thamiris Candreva Mariah B. P. dos Anjos Hosana G. Rodrigues |
| author_sort | Jéssica R. Silva |
| collection | DOAJ |
| description | Wound healing is an evolutionarily conserved process that is essential for species survival. Wound healing involves a series of biochemical and cellular events that are tightly controlled, divided into 3 concomitant and overlapping phases: inflammation, proliferation, and remodelling. Poor wound healing or a chronic wound represents a silent epidemic that affects billions of people worldwide. Considering the involvement of immune cells in its resolution, recent studies are focused on investigating the roles of immune nutrients such as amino acids, minerals, and fatty acids on wound healing. Among the fatty acids, much attention has been given to omega-6 (ω-6) fatty acids since they can modulate cell migration and proliferation, phagocytic capacity, and production of inflammatory mediators. The present review summarizes current knowledge about the role of ω-6 fatty acids in the wound healing context. |
| format | Article |
| id | doaj-art-a5a8a95765634a8dbbe31b48de6faf98 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-a5a8a95765634a8dbbe31b48de6faf982025-02-03T06:05:08ZengWileyMediators of Inflammation0962-93511466-18612018-01-01201810.1155/2018/25039502503950Wound Healing and Omega-6 Fatty Acids: From Inflammation to RepairJéssica R. Silva0Beatriz Burger1Carolina M. C. Kühl2Thamiris Candreva3Mariah B. P. dos Anjos4Hosana G. Rodrigues5Laboratory of Nutrients and Tissue Repair, School of Applied Sciences, University of Campinas, Limeira, SP, BrazilLaboratory of Nutrients and Tissue Repair, School of Applied Sciences, University of Campinas, Limeira, SP, BrazilLaboratory of Nutrients and Tissue Repair, School of Applied Sciences, University of Campinas, Limeira, SP, BrazilLaboratory of Nutrients and Tissue Repair, School of Applied Sciences, University of Campinas, Limeira, SP, BrazilLaboratory of Nutrients and Tissue Repair, School of Applied Sciences, University of Campinas, Limeira, SP, BrazilLaboratory of Nutrients and Tissue Repair, School of Applied Sciences, University of Campinas, Limeira, SP, BrazilWound healing is an evolutionarily conserved process that is essential for species survival. Wound healing involves a series of biochemical and cellular events that are tightly controlled, divided into 3 concomitant and overlapping phases: inflammation, proliferation, and remodelling. Poor wound healing or a chronic wound represents a silent epidemic that affects billions of people worldwide. Considering the involvement of immune cells in its resolution, recent studies are focused on investigating the roles of immune nutrients such as amino acids, minerals, and fatty acids on wound healing. Among the fatty acids, much attention has been given to omega-6 (ω-6) fatty acids since they can modulate cell migration and proliferation, phagocytic capacity, and production of inflammatory mediators. The present review summarizes current knowledge about the role of ω-6 fatty acids in the wound healing context.http://dx.doi.org/10.1155/2018/2503950 |
| spellingShingle | Jéssica R. Silva Beatriz Burger Carolina M. C. Kühl Thamiris Candreva Mariah B. P. dos Anjos Hosana G. Rodrigues Wound Healing and Omega-6 Fatty Acids: From Inflammation to Repair Mediators of Inflammation |
| title | Wound Healing and Omega-6 Fatty Acids: From Inflammation to Repair |
| title_full | Wound Healing and Omega-6 Fatty Acids: From Inflammation to Repair |
| title_fullStr | Wound Healing and Omega-6 Fatty Acids: From Inflammation to Repair |
| title_full_unstemmed | Wound Healing and Omega-6 Fatty Acids: From Inflammation to Repair |
| title_short | Wound Healing and Omega-6 Fatty Acids: From Inflammation to Repair |
| title_sort | wound healing and omega 6 fatty acids from inflammation to repair |
| url | http://dx.doi.org/10.1155/2018/2503950 |
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