Multiplexed phosphoproteomics of low cell numbers using SPARCE

Abstract Understanding cellular diversity and disease mechanisms requires a global analysis of proteins and their modifications. While next-generation sequencing has advanced our understanding of cellular heterogeneity, it fails to capture downstream signalling networks. Ultrasensitive mass spectrom...

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Bibliographic Details
Main Authors: Emily J. Gaizley, Xiuyuan Chen, Amandeep Bhamra, Tariq Enver, Silvia Surinova
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08068-x
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