Chorein deficiency promotes ferroptosis

Chorein deficiency promotes ferroptosis

Ferroptosis is a type of programmed cell death owed to an intracellular accumulation of iron resulting in the generation reactive oxygen species, which in turn can cause peroxidation of plasma membrane lipids and ultimately result in cell death. We investigated the potential involvement of VPS13A de...

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Bibliographic Details
Main Authors: Yoshiaki Nishizawa, Hitoshi Sakimoto, Omi Nagata, Natsuki Sasaki, Yuka Urata, Kaoru Arai, Hanae Hiwatashi, Izumi Yokoyama, Shosei Kishida, Akira Sano, Masayuki Nakamura
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:FEBS Open Bio
Subjects:
chorea‐acanthocytosis
chorein
ferroptosis
ferrous iron
glutathione peroxidase 4
VPS13A
Online Access:https://doi.org/10.1002/2211-5463.13870
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https://doi.org/10.1002/2211-5463.13870

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