Hyperhomocysteinaemia aggravates periodontitis by suppressing the Nrf2/HO-1 signalling pathway

Hyperhomocysteinaemia aggravates periodontitis by suppressing the Nrf2/HO-1 signalling pathway

Periodontitis, a common dental illness, causes periodontal tissue inflammation and irreversible bone loss, inevitably resulting in tooth loss. Hyperhomocysteinaemia (HHcy), defined as blood total homocysteine (Hcy) levels greater than 15 µmol/L, is linked to increased cardiovascular disease risk. Mo...

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Bibliographic Details
Main Authors: Kaiqiang Yang, Yuting Yang, Ting Long, Xiaoxue Wang, Yeke Chen, Chenjiang He, Li Li, Xinbo Yang, Meixiu Jiang, Yichen Hu, Fang Dai, Li Song
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Redox Report
Subjects:
Periodontitis
oxidative stress
ROS
Nrf2
bone loss
inflammation
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2025.2475691
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https://www.tandfonline.com/doi/10.1080/13510002.2025.2475691

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