Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database
Introduction. Regional differences for fracture risk of US Hispanics may vary by national origin. In California, where a majority of the Hispanic population is of Mexican descent, it is of interest to compare the FRAX absolute risk using the US Hispanic and Mexico databases. Methods. We collected FR...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Journal of Osteoporosis |
| Online Access: | http://dx.doi.org/10.4061/2011/531359 |
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| _version_ | 1832559781520343040 |
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| author | Keaton M. Nasser Augusto Focil Stuart L. Silverman |
| author_facet | Keaton M. Nasser Augusto Focil Stuart L. Silverman |
| author_sort | Keaton M. Nasser |
| collection | DOAJ |
| description | Introduction. Regional differences for fracture risk of US Hispanics may vary by national origin. In California, where a majority of the Hispanic population is of Mexican descent, it is of interest to compare the FRAX absolute risk using the US Hispanic and Mexico databases.
Methods. We collected FRAX risk factor data from 134 women of Mexican descent in southern California. The FRAX risk score was calculated using the US Hispanic and Mexican databases, using the NOF guidelines for osteoporosis to compare the number of patients that would be selected for treatment.
Results. The 10-year absolute risk of major osteoporotic fracture among women of Mexican descent using the US Hispanic database was 4.82 ± 5.03 (95% CI 3.97–5.67) compared to 4.86 ± 4.72 (CI 3.98–5.44) using the Mexico database (P=.94). The 10-year risk for hip fracture was 0.86 ± 1.78 (CI .56–1.16) compared to 1.12 ± 1.97 (CI .79–1.45, P=.26). The mean conformity for meeting the interventional threshold by either risk score was 94.8%. Conclusion. The comparison between the FRAX databases demonstrates a similarity in the absolute risk of major osteoporotic fracture. Differences are noted in the absolute number of hip fracture subjects at risk, but there is a high rate of conformity. |
| format | Article |
| id | doaj-art-a546e67b8797470692957188071be7f8 |
| institution | Kabale University |
| issn | 2042-0064 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Osteoporosis |
| spelling | doaj-art-a546e67b8797470692957188071be7f82025-02-03T01:29:14ZengWileyJournal of Osteoporosis2042-00642011-01-01201110.4061/2011/531359531359Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico DatabaseKeaton M. Nasser0Augusto Focil1Stuart L. Silverman2Osteoporosis Medical Center, 8641 Wilshire Boulevard, Suite 301, Beverly Hills, CA 90211, USACalifornia Hispanic Osteoporosis Foundation, Oxnard, CA 93030, USAOsteoporosis Medical Center, 8641 Wilshire Boulevard, Suite 301, Beverly Hills, CA 90211, USAIntroduction. Regional differences for fracture risk of US Hispanics may vary by national origin. In California, where a majority of the Hispanic population is of Mexican descent, it is of interest to compare the FRAX absolute risk using the US Hispanic and Mexico databases. Methods. We collected FRAX risk factor data from 134 women of Mexican descent in southern California. The FRAX risk score was calculated using the US Hispanic and Mexican databases, using the NOF guidelines for osteoporosis to compare the number of patients that would be selected for treatment. Results. The 10-year absolute risk of major osteoporotic fracture among women of Mexican descent using the US Hispanic database was 4.82 ± 5.03 (95% CI 3.97–5.67) compared to 4.86 ± 4.72 (CI 3.98–5.44) using the Mexico database (P=.94). The 10-year risk for hip fracture was 0.86 ± 1.78 (CI .56–1.16) compared to 1.12 ± 1.97 (CI .79–1.45, P=.26). The mean conformity for meeting the interventional threshold by either risk score was 94.8%. Conclusion. The comparison between the FRAX databases demonstrates a similarity in the absolute risk of major osteoporotic fracture. Differences are noted in the absolute number of hip fracture subjects at risk, but there is a high rate of conformity.http://dx.doi.org/10.4061/2011/531359 |
| spellingShingle | Keaton M. Nasser Augusto Focil Stuart L. Silverman Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database Journal of Osteoporosis |
| title | Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database |
| title_full | Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database |
| title_fullStr | Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database |
| title_full_unstemmed | Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database |
| title_short | Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database |
| title_sort | comparison of frax scores of southern california females of mexican descent using us hispanic and mexico database |
| url | http://dx.doi.org/10.4061/2011/531359 |
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