Paroxysmal Nocturnal Hemoglobinuria in Patients with Aplastic Anemia: Challenges, Characteristics, and Analysis of Clinical Experience

Paroxysmal Nocturnal Hemoglobinuria in Patients with Aplastic Anemia: Challenges, Characteristics, and Analysis of Clinical Experience

Background & Aims. Paroxysmal nocturnal hemoglobinuria (PNH) is a disease caused by an acquired clonal disorder of hematopoietic stem cells with clone cell membrane hypersensitivity to the complement. PNH can exist as an independent disease and can also be associated with other pathological cond...

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Bibliographic Details
Main Authors: ER Shilova, TV Glazanova, ZhV Chubukina, OE Rozanova, MN Zenina, AV Seltser, VI Rugal, VA Balashova, VA Kobilyanskaya, II Krobinets, VYu Udal’eva, II Zotova, LV Stelmashenko, NA Romanenko, TB Zamotina, IV Khorsheva, SV Voloshin
Format: Article
Language:Russian
Published: Practical Medicine Publishing House 2019-05-01
Series:Клиническая онкогематология
Subjects:
aplastic anemia
paroxysmal nocturnal hemoglobinuria
pnh phenotype
pnh clone
targeted therapy
c3-mediated hemolysis
Online Access: http://bloodjournal.ru/wp-content/uploads/2019/06/11.pdf
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http://bloodjournal.ru/wp-content/uploads/2019/06/11.pdf

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