IL-1β stimulates ADAMTS9 expression and contributes to preterm prelabor rupture of membranes

IL-1β stimulates ADAMTS9 expression and contributes to preterm prelabor rupture of membranes

Abstract Background Preterm prelabor rupture of membranes (pPROM) is a leading cause of neonatal morbidity and mortality. While intra-amniotic infection is a well-established driver of pPROM, the role of sterile intra-amniotic inflammation remains unclear. Recent evidence suggests that interleukin-1...

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Main Authors: Jiasong Cao, Yixin Wang, Qimei Lin, Shuqi Wang, Yongmei Shen, Lei Zhang, Wen Li, Ling Chen, Chunliu Liu, Shihan Yao, Ling Shuai, Xu Chen, Zongjin Li, Ying Chang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Cell Communication and Signaling
Subjects:
Preterm prelabor rupture of fetal membranes
Interleukin-1 beta
ADAMTS9
NF-kappa B
Protein O-fucosyltransferase 2
Online Access:https://doi.org/10.1186/s12964-025-02120-3
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https://doi.org/10.1186/s12964-025-02120-3

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