With great power, comes great responsibility: the importance of broadly measuring Fc-mediated effector function early in the antibody development process
The field of antibody therapeutics is rapidly growing, with over 210 antibodies currently approved or in regulatory review and ~ 1,250 antibodies in clinical development. Antibodies are highly versatile molecules that, with strategic design of their antigen-binding domain (Fab) and the domain respon...
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Main Authors: | Silvia Crescioli, Shashi Jatiani, Lenny Moise |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2025-12-01
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Series: | mAbs |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/19420862.2025.2453515 |
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