Effect of Amlodipine on hepatitis C virus induced portal hypertension in children with acute leukemia
Background: Aim: Results: Conclusion: .key words :hepatitis C,leukemia, pediatrics Treatment with Amlodipine can be used to control portal hypertension in leukemic children having hepatitis c virus induced portal hypertension. From this study, we found that Amlodipine was effective in reducing the...
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| Language: | English |
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PAGEPress Publications
2014-08-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
| Online Access: | https://mjhid.org/index.php/mjhid/article/view/1807 |
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| author | Maysaa El Sayed Zaki |
| author_facet | Maysaa El Sayed Zaki |
| author_sort | Maysaa El Sayed Zaki |
| collection | DOAJ |
| description | Background:
Aim:
Results:
Conclusion:
.key words :hepatitis C,leukemia, pediatrics
Treatment with Amlodipine can be used to control portal hypertension in leukemic children having hepatitis c virus induced portal hypertension. From this study, we found that Amlodipine was effective in reducing the elevated portal blood pressure to normal level in doses which doesnot interfer with mechanism of action of chemotherapy In the present study we tested the effect of Amlodipine on children of acute lymphoblastic leukemia having portal hypertention secondary to hepatitis c infection during maintenance chemotherapy Children with acute leukemia are at high risk of hepatitis C infection, either by imunosuppression secondary to chemotherapy or by multiple transfusions of blood products during the course of the disease. Hepatitis C constitute a major problem during management of acute leukemias due to resultant Portal hypertension, or bleeding esophageal varices. Chronic HCV infection is a major cause of liver cirrhosis and hepatocellular carcinoma in leukemic survivors. |
| format | Article |
| id | doaj-art-a4bf4be8a7d74b9c8b96ada8bd5a89f1 |
| institution | OA Journals |
| issn | 2035-3006 |
| language | English |
| publishDate | 2014-08-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-a4bf4be8a7d74b9c8b96ada8bd5a89f12025-08-20T01:47:48ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062014-08-011Effect of Amlodipine on hepatitis C virus induced portal hypertension in children with acute leukemiaMaysaa El Sayed Zaki0Professor of clinical pathologyBackground: Aim: Results: Conclusion: .key words :hepatitis C,leukemia, pediatrics Treatment with Amlodipine can be used to control portal hypertension in leukemic children having hepatitis c virus induced portal hypertension. From this study, we found that Amlodipine was effective in reducing the elevated portal blood pressure to normal level in doses which doesnot interfer with mechanism of action of chemotherapy In the present study we tested the effect of Amlodipine on children of acute lymphoblastic leukemia having portal hypertention secondary to hepatitis c infection during maintenance chemotherapy Children with acute leukemia are at high risk of hepatitis C infection, either by imunosuppression secondary to chemotherapy or by multiple transfusions of blood products during the course of the disease. Hepatitis C constitute a major problem during management of acute leukemias due to resultant Portal hypertension, or bleeding esophageal varices. Chronic HCV infection is a major cause of liver cirrhosis and hepatocellular carcinoma in leukemic survivors.https://mjhid.org/index.php/mjhid/article/view/1807 |
| spellingShingle | Maysaa El Sayed Zaki Effect of Amlodipine on hepatitis C virus induced portal hypertension in children with acute leukemia Mediterranean Journal of Hematology and Infectious Diseases |
| title | Effect of Amlodipine on hepatitis C virus induced portal hypertension in children with acute leukemia |
| title_full | Effect of Amlodipine on hepatitis C virus induced portal hypertension in children with acute leukemia |
| title_fullStr | Effect of Amlodipine on hepatitis C virus induced portal hypertension in children with acute leukemia |
| title_full_unstemmed | Effect of Amlodipine on hepatitis C virus induced portal hypertension in children with acute leukemia |
| title_short | Effect of Amlodipine on hepatitis C virus induced portal hypertension in children with acute leukemia |
| title_sort | effect of amlodipine on hepatitis c virus induced portal hypertension in children with acute leukemia |
| url | https://mjhid.org/index.php/mjhid/article/view/1807 |
| work_keys_str_mv | AT maysaaelsayedzaki effectofamlodipineonhepatitiscvirusinducedportalhypertensioninchildrenwithacuteleukemia |