Atoh8 expression inhibition promoted osteogenic differentiation of ADSCs and inhibited cell proliferation in vitro and rat bone defect models

Atoh8 expression inhibition promoted osteogenic differentiation of ADSCs and inhibited cell proliferation in vitro and rat bone defect models

Stem cell-based bone tissue engineering offers a promising approach for treating oral and cranio-maxillofacial bone defects. This study investigated the role of Atoh8, a key regulator in various cells, in the osteogenic potential of adipose-derived stem cells (ADSCs). ADSCs transfected with small in...

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Bibliographic Details
Main Authors: Zian Yi, Shuang Song, Yuxin Bai, Guanhua Zhang, Yuxi Wang, Zijun Chen, Xuefeng Chen, Banglian Deng, Xiangdong Liu, Zuolin Jin
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Adipocyte
Subjects:
Atoh8
adipose-derived stem cells
osteogenic differentiation
bone repair
stem cell transplantation
Online Access:https://www.tandfonline.com/doi/10.1080/21623945.2025.2494089
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