Interplay between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-Presentation Psychotic Disorder: A Pilot Study.

Interplay between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-Presentation Psychotic Disorder: A Pilot Study.

A history of childhood adversity is associated with psychotic disorder, with an increase in risk according to number or severity of exposures. However, it is not known why only some exposed individuals go on to develop psychosis. One possibility is pre-existing genetic vulnerability. Research on gen...

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Bibliographic Details
Main Authors: Antonella Trotta, Conrad Iyegbe, Marta Di Forti, Pak C Sham, Desmond D Campbell, Stacey S Cherny, Valeria Mondelli, Katherine J Aitchison, Robin M Murray, Evangelos Vassos, Helen L Fisher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0163319&type=printable
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