Contemporary medical therapy, sex-specific characteristics, and outcomes of patients with non-ischemic cardiomyopathy: a prespecified interim analysis of the BIO-LIBRA studyResearch in context

Contemporary medical therapy, sex-specific characteristics, and outcomes of patients with non-ischemic cardiomyopathy: a prespecified interim analysis of the BIO-LIBRA studyResearch in context

Summary: Background: Contemporary data on characteristics, medical therapy, and outcomes in non-ischemic cardiomyopathy (NICM) with implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy defibrillator (CRT-D) are lacking, and the role of sex remains unexplored due to hist...

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Main Authors: Valentina Kutyifa, Luigi Di Biase, Karthik Venkatesh Prasad, Vilma Torres, Aaron Hesselson, Craig J. McCotter, Gregory Harris, Karlene Cox, Susan Schleede, E. Kevin Heist, Scott McNitt, Mary W. Brown, Crystal Miller, Christopher A. Beck, Jeanne Poole, Karthik Prasad, David Frazier, Kristin Ellison, Jonathan Dukes, Jihn Han, Paul Gerczuk, Gery Tomassoni, Matthew Sellers, Theofanie Mela, Stavros Mountantonakis, Mountantonakis, Bryan Frain, Parash Pokharel, Srinivas Rajsheker, George Thomas, J. Matt Brunson, Omar Kahaly, Samuel Johnston, Luis Garcia, Rakesh Latchamsetty, David Huang, Zaid Aziz, David Rodak, Soraya Samii, Jonathan Hobson, Sherry Saxonhouse, Vipul Shah, Harish Manyam, Robert P. Robichaux, Jr., Christopher Pierce, Richard Vest, Christian Ngo, Michael Yarnoz, Natalie Bradford, Rajasekhar Nekkanti, Margot Vloka, Uma Srivatsa, Chandra Bomma, Khaled Awad, Sei Iwai, Shane Rowan, Matthew Sevensma, Michael Drucker, Toshimasa Okabe, Anthony Ochoa, Leon Feldman, Gioia Turitto
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:EClinicalMedicine
Subjects:
Ventricular tachyarrhythmias
Sex differences
Left ventricular dysfunction
Implantable cardioverter defibrillator
Cardiac resynchronization therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S258953702500269X
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