Hospitalization due to pneumococcal disease in the Unified Health System in Brazil: A retrospective analysis of administrative data
Introduction: Community-Acquired Pneumonia (CAP) caused by pneumococcus and Invasive Pneumococcal Disease (IPD) pose a substantial economic burden on health systems. The objective of the present study is to explore hospitalization costs of pneumococcal disease in the public health system in Brazil,...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Brazilian Journal of Infectious Diseases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1413867024007657 |
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| author | Daniela V. Pachito Mauricio Longato Guilherme Cordeiro Paulo H.R.F. Almeida Ricardo Macarini Ferreira Ana Paula N. Burian |
| author_facet | Daniela V. Pachito Mauricio Longato Guilherme Cordeiro Paulo H.R.F. Almeida Ricardo Macarini Ferreira Ana Paula N. Burian |
| author_sort | Daniela V. Pachito |
| collection | DOAJ |
| description | Introduction: Community-Acquired Pneumonia (CAP) caused by pneumococcus and Invasive Pneumococcal Disease (IPD) pose a substantial economic burden on health systems. The objective of the present study is to explore hospitalization costs of pneumococcal disease in the public health system in Brazil, the Unified Health System. Methods: Retrospective analysis of administrative data on hospitalized cases of pneumococcal disease from January 2019 to July 2023. Hospitalization cases recorded with ICD-10 codes of CAP due to S. pneumoniae and IPD were retrieved from DATASUS, the inpatient information system of the Unified Health System in Brazil. Costs were converted to US dollars by Using Purchasing Power Parity (USD-PPP). Absolute number of hospitalizations, costs of hospitalizations and healthcare resource utilization were presented descriptively. The annual cost estimate was calculated. Differences in costs by type of clinical presentation and age group were assessed. Factors associated with higher costs were explored by multiple linear regression models. Results: A total of 22,498 hospitalization episodes were analyzed. Total cost of hospitalizations was USD-PPP 13,958,959 (BRL 34,659,578) with an annual mean estimate of USD-PPP 3,045,591 (BRL 7,562,090). Cost per hospitalization episode was significantly higher for meningitis, followed by septicemia, CAP and arthritis, with median values ranging from USD-PPP 190.93 to 615.14 (BRL 476.20 to 1529.02). (Kruskal-Wallis χ2 = 6473, df = 3, p-value < 0.0001). Costs were significantly higher among individuals aged 60-years and older. (Kruskal-Wallis test; χ2 = 773.53; df = 2, p-value < 0.0001). There were differences in age at hospitalization, length of stay, and ICU utilization among types of clinical presentations. Conclusions: Our findings reveal the economic burden associated with pneumococcal disease in the Unified Health System in Brazil. Hospitalization costs were higher for cases of meningitis and among individuals aged 60-years and above. |
| format | Article |
| id | doaj-art-a465d3ce8dd44d188f55d76ed89eff98 |
| institution | Kabale University |
| issn | 1413-8670 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Infectious Diseases |
| spelling | doaj-art-a465d3ce8dd44d188f55d76ed89eff982025-01-26T05:03:33ZengElsevierBrazilian Journal of Infectious Diseases1413-86702025-01-01291104482Hospitalization due to pneumococcal disease in the Unified Health System in Brazil: A retrospective analysis of administrative dataDaniela V. Pachito0Mauricio Longato1Guilherme Cordeiro2Paulo H.R.F. Almeida3Ricardo Macarini Ferreira4Ana Paula N. Burian5Pfizer Brazil, São Paulo, SP, Brazil; Corresponding author.Analytix, São Paulo, SP, BrazilAnalytix, São Paulo, SP, BrazilPfizer Brazil, São Paulo, SP, BrazilPfizer Brazil, São Paulo, SP, BrazilSecretaria Estadual de Saúde do Espírito Santo, Vitória, ES, BrazilIntroduction: Community-Acquired Pneumonia (CAP) caused by pneumococcus and Invasive Pneumococcal Disease (IPD) pose a substantial economic burden on health systems. The objective of the present study is to explore hospitalization costs of pneumococcal disease in the public health system in Brazil, the Unified Health System. Methods: Retrospective analysis of administrative data on hospitalized cases of pneumococcal disease from January 2019 to July 2023. Hospitalization cases recorded with ICD-10 codes of CAP due to S. pneumoniae and IPD were retrieved from DATASUS, the inpatient information system of the Unified Health System in Brazil. Costs were converted to US dollars by Using Purchasing Power Parity (USD-PPP). Absolute number of hospitalizations, costs of hospitalizations and healthcare resource utilization were presented descriptively. The annual cost estimate was calculated. Differences in costs by type of clinical presentation and age group were assessed. Factors associated with higher costs were explored by multiple linear regression models. Results: A total of 22,498 hospitalization episodes were analyzed. Total cost of hospitalizations was USD-PPP 13,958,959 (BRL 34,659,578) with an annual mean estimate of USD-PPP 3,045,591 (BRL 7,562,090). Cost per hospitalization episode was significantly higher for meningitis, followed by septicemia, CAP and arthritis, with median values ranging from USD-PPP 190.93 to 615.14 (BRL 476.20 to 1529.02). (Kruskal-Wallis χ2 = 6473, df = 3, p-value < 0.0001). Costs were significantly higher among individuals aged 60-years and older. (Kruskal-Wallis test; χ2 = 773.53; df = 2, p-value < 0.0001). There were differences in age at hospitalization, length of stay, and ICU utilization among types of clinical presentations. Conclusions: Our findings reveal the economic burden associated with pneumococcal disease in the Unified Health System in Brazil. Hospitalization costs were higher for cases of meningitis and among individuals aged 60-years and above.http://www.sciencedirect.com/science/article/pii/S1413867024007657Pneumococcal infectionsHealth care economics and organizationsCosts and cost analysisUnified health system |
| spellingShingle | Daniela V. Pachito Mauricio Longato Guilherme Cordeiro Paulo H.R.F. Almeida Ricardo Macarini Ferreira Ana Paula N. Burian Hospitalization due to pneumococcal disease in the Unified Health System in Brazil: A retrospective analysis of administrative data Brazilian Journal of Infectious Diseases Pneumococcal infections Health care economics and organizations Costs and cost analysis Unified health system |
| title | Hospitalization due to pneumococcal disease in the Unified Health System in Brazil: A retrospective analysis of administrative data |
| title_full | Hospitalization due to pneumococcal disease in the Unified Health System in Brazil: A retrospective analysis of administrative data |
| title_fullStr | Hospitalization due to pneumococcal disease in the Unified Health System in Brazil: A retrospective analysis of administrative data |
| title_full_unstemmed | Hospitalization due to pneumococcal disease in the Unified Health System in Brazil: A retrospective analysis of administrative data |
| title_short | Hospitalization due to pneumococcal disease in the Unified Health System in Brazil: A retrospective analysis of administrative data |
| title_sort | hospitalization due to pneumococcal disease in the unified health system in brazil a retrospective analysis of administrative data |
| topic | Pneumococcal infections Health care economics and organizations Costs and cost analysis Unified health system |
| url | http://www.sciencedirect.com/science/article/pii/S1413867024007657 |
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