Single nucleotide variants in transcription factors associate more tightly with phenotype than with gene expression.

Mapping the polymorphisms responsible for variation in gene expression, known as Expression Quantitative Trait Loci (eQTL), is a common strategy for investigating the molecular basis of disease. Despite numerous eQTL studies, the relationship between the explanatory power of variants on gene express...

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Bibliographic Details
Main Authors: Priya Sudarsanam, Barak A Cohen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004325&type=printable
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