Single-cell RNA sequencing of bone marrow reveals the immune response mechanisms of lymphocytes under avian leukosis virus subgroup J infection

Single-cell RNA sequencing of bone marrow reveals the immune response mechanisms of lymphocytes under avian leukosis virus subgroup J infection

Avian Leukosis Virus (ALV) can induce tumorigenesis and immune suppression by acting on lymphocytes in the bone marrow. In this study, single-cell RNA sequencing (scRNA-seq) was used to analyze chicken bone marrow lymphocytes under Avian Leukosis Virus subtype J (ALV-J) infection. Using subgroup-spe...

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Bibliographic Details
Main Authors: Cheng Liu, Yu Zhang, Ruyu Liao, Lecheng Wang, Xinyi Zhou, Min Tan, Keyun Xu, Haiwei Wang, Qigui Wang, Yongju Zhao, Zhifu Cui, Xi Lan
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Poultry Science
Subjects:
ALV-J
scRNA-seq
Bone marrow
Lymphocytes
Immune suppression
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579125002342
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