Supersulfides contribute to joint homeostasis and bone regeneration

Supersulfides contribute to joint homeostasis and bone regeneration

The physiological functions of supersulfides, inorganic and organic sulfides with sulfur catenation, have been extensively studied. Their synthesis is mainly mediated by mitochondrial cysteinyl-tRNA synthetase (CARS2) that functions as a principal cysteine persulfide synthase. This study aimed to in...

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Bibliographic Details
Main Authors: Miki Maemura, Masanobu Morita, Seiryo Ogata, Yoichi Miyamoto, Tomoaki Ida, Kazuhiro Shibusaka, Soichiro Negishi, Masahiro Hosonuma, Taku Saito, Jun Yoshitake, Tsuyoshi Takata, Tetsuro Matsunaga, Eikan Mishima, Uladzimir Barayeu, Takaaki Akaike, Fumiko Yano
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Redox Biology
Subjects:
Supersulfides
Cysteinyl-tRNA synthetase
Osteoarthritis
Bone regeneration
Glutathione trisulfide
Ferroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725000588
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