Development and testing of AAV-delivered single-chain variable fragments for the treatment of methamphetamine abuse.

Development and testing of AAV-delivered single-chain variable fragments for the treatment of methamphetamine abuse.

Methamphetamine (METH) substance abuse disorders have major impact on society, yet no medications have proven successful at preventing METH relapse or cravings. Anti-METH monoclonal antibodies can reduce METH brain concentrations; however, this therapy has limitations, including the need for repeate...

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Bibliographic Details
Main Authors: Charles E Hay, Guillermo A Gonzalez, Laura E Ewing, E Elizabeth Reichard, Michael D Hambuchen, Nisha Nanaware-Kharade, Sinthia Alam, Chris T Bolden, S Michael Owens, Paris Margaritis, Eric C Peterson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0200060&type=printable
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