Telmisartan modulates exercise responses in peripheral artery disease: Analyses of skeletal muscle from the TELEX Trial

Telmisartan modulates exercise responses in peripheral artery disease: Analyses of skeletal muscle from the TELEX Trial

Objective: In people with peripheral artery disease (PAD), the Telmisartan Plus Exercise to Improve Functioning in Peripheral Artery Disease (TELEX) randomized clinical trial tested whether telmisartan (TEL), with or without exercise, significantly improved 6-minute walk distance at 6-month follow-u...

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Main Authors: Kate Kosmac, PhD, Jai K. Joshi, BS, Mary M. McDermott, MD, Jada C. Stewart, BS, Dongxue Zhang, MS, Shujun Xu, MS, Karen J. Ho, MD, Robert Sufit, MD, Luigi Ferrucci, MD, Charlotte A. Peterson, PhD, Ahmed Ismaeel, PhD
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:JVS - Vascular Science
Subjects:
Alpha-smooth muscle actin
Cell deconvolution
Digital spatial profiling
Myostatin
Spatial transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S266635032500015X
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