Integrated 16S rDNA-Seq and metabolomics reveal seasonal dynamics of gut microbial–SCFA–immune crosstalk in diarrheic calves

Integrated 16S rDNA-Seq and metabolomics reveal seasonal dynamics of gut microbial–SCFA–immune crosstalk in diarrheic calves

IntroductionNeonatal calf diarrhea incidence varies seasonally, increasing during climatic fluctuations. This study investigated body weight and size, immune function, intestinal permeability, rectal microbiota, and short-chain fatty acid (SCFA) levels in diarrheal and healthy lactating calves acros...

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Bibliographic Details
Main Authors: Qianqian Wang, Qicheng Lu, Yaqin Tang, Qiuyan Li, Peiyun Gao, Shaoyang Pang, Wenju Zhang, Cunxi Nie, Junli Niu, Xiaoling Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Veterinary Science
Subjects:
lactating calves
diarrhea
seasons
intestinal permeability
rectal flora
short-chain fatty acids
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1615310/full
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