Embracing Integrative Multiomics Approaches

As “-omics” data technology advances and becomes more readily accessible to address complex biological questions, increasing amount of cross “-omics” dataset is inspiring the use and development of integrative bioinformatics analysis. In the current review, we discuss multiple options for integratin...

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Main Authors: Daniel M. Rotroff, Alison A. Motsinger-Reif
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/2016/1715985
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author Daniel M. Rotroff
Alison A. Motsinger-Reif
author_facet Daniel M. Rotroff
Alison A. Motsinger-Reif
author_sort Daniel M. Rotroff
collection DOAJ
description As “-omics” data technology advances and becomes more readily accessible to address complex biological questions, increasing amount of cross “-omics” dataset is inspiring the use and development of integrative bioinformatics analysis. In the current review, we discuss multiple options for integrating data across “-omes” for a range of study designs. We discuss established methods for such analysis and point the reader to in-depth discussions for the various topics. Additionally, we discuss challenges and new directions in the area.
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institution Kabale University
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spelling doaj-art-a331d219f0e74a45baa3e3f888012fd92025-02-03T05:46:03ZengWileyInternational Journal of Genomics2314-436X2314-43782016-01-01201610.1155/2016/17159851715985Embracing Integrative Multiomics ApproachesDaniel M. Rotroff0Alison A. Motsinger-Reif1Bioinformatics Research Center, North Carolina State University, Raleigh, NC 27607, USABioinformatics Research Center, North Carolina State University, Raleigh, NC 27607, USAAs “-omics” data technology advances and becomes more readily accessible to address complex biological questions, increasing amount of cross “-omics” dataset is inspiring the use and development of integrative bioinformatics analysis. In the current review, we discuss multiple options for integrating data across “-omes” for a range of study designs. We discuss established methods for such analysis and point the reader to in-depth discussions for the various topics. Additionally, we discuss challenges and new directions in the area.http://dx.doi.org/10.1155/2016/1715985
spellingShingle Daniel M. Rotroff
Alison A. Motsinger-Reif
Embracing Integrative Multiomics Approaches
International Journal of Genomics
title Embracing Integrative Multiomics Approaches
title_full Embracing Integrative Multiomics Approaches
title_fullStr Embracing Integrative Multiomics Approaches
title_full_unstemmed Embracing Integrative Multiomics Approaches
title_short Embracing Integrative Multiomics Approaches
title_sort embracing integrative multiomics approaches
url http://dx.doi.org/10.1155/2016/1715985
work_keys_str_mv AT danielmrotroff embracingintegrativemultiomicsapproaches
AT alisonamotsingerreif embracingintegrativemultiomicsapproaches