Cardioprotective effects of naringin in a type 2 diabetes rodent model by reducing calcium overload and oxidative stress

Cardioprotective effects of naringin in a type 2 diabetes rodent model by reducing calcium overload and oxidative stress

IntroductionDiabetic cardiomyopathy (DCM) is characterized by structural and functional alterations in the heart muscle, occurring independently of other cardiovascular risk factors such as dyslipidemia, hypertension, or coronary artery disease. Despite efforts to manage type 2 diabetes (T2D) and it...

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Bibliographic Details
Main Authors: Arkady Uryash, Alfredo Mijares, Jose Miguel Eltit, Jose A. Adams, Jose R. Lopez
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pharmacology
Subjects:
cardiomyocytes
diabetes
naringin
calcium
diabetic cardiomyopathy
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1621356/full
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