Targeting DKK3 to remodel tumor immune microenvironment and enhance cancer immunotherapy

Abstract Cancer immunotherapy such as immune checkpoint blockade (ICB) therapy has made important breakthroughs in cancer treatment, however, currently only parts of cancer patients benefit from ICB therapy. The suppressive tumor immune microenvironment (TIME) impedes the treatment response of immun...

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Bibliographic Details
Main Authors: Kai Shi, Yan Zhao, Hao Ye, Xiaoming Zhu, Zhenghai Chen
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-025-14075-2
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