Review of Metabolic Surgery for Type 2 Diabetes in Patients with a BMI < 35 kg/m2

Bariatric/metabolic surgery is considered an accepted treatment option for type 2 diabetes mellitus (T2DM) with body mass index (BMI)  ≧  35 kg/m2. Mounting evidence also shows that metabolic surgery is effective for T2DM with BMI  <  35 kg/m2. To evaluate current status of metabolic surgery, we...

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Main Authors: Hideharu Shimizu, Poochong Timratana, Philip R. Schauer, Tomasz Rogula
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Obesity
Online Access:http://dx.doi.org/10.1155/2012/147256
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author Hideharu Shimizu
Poochong Timratana
Philip R. Schauer
Tomasz Rogula
author_facet Hideharu Shimizu
Poochong Timratana
Philip R. Schauer
Tomasz Rogula
author_sort Hideharu Shimizu
collection DOAJ
description Bariatric/metabolic surgery is considered an accepted treatment option for type 2 diabetes mellitus (T2DM) with body mass index (BMI)  ≧  35 kg/m2. Mounting evidence also shows that metabolic surgery is effective for T2DM with BMI  <  35 kg/m2. To evaluate current status of metabolic surgery, we reviewed the available clinical studies which described surgical treatment for T2DM with mean BMI  <  35 kg/m2. 18 studies with 477 patients were identified. 30% of the patients was insulin users. The follow-up period ranged from 6 to 216 months. The weight loss effect was reasonable, not excessive. Mean BMI decreased from 30.4 to 24.8 kg/m2. Remission of T2DM was achieved in 64.7% of the patients with fasting plasma glucose and glycated hemoglobin approaching slightly above normal range. Clinical T2DM status was an important factor when selecting the eligible candidates for metabolic surgery. Postoperative complication rate of 10.3% with mortality of 0% in the studies has been acceptable. Even though it would be premature at this point to state that metabolic surgery is an accepted treatment option for T2DM with BMI < 35 kg/m2, it is clear that a high proportion of T2DM patients will derive substantial benefit from metabolic surgery.
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spelling doaj-art-a3059a63d9604d9fb49cd312ed4113102025-02-03T05:46:29ZengWileyJournal of Obesity2090-07082090-07162012-01-01201210.1155/2012/147256147256Review of Metabolic Surgery for Type 2 Diabetes in Patients with a BMI < 35 kg/m2Hideharu Shimizu0Poochong Timratana1Philip R. Schauer2Tomasz Rogula3M61 Cleveland Clinic, Bariatric and Metabolic Institute, 9500 Euclid Avenue, Cleveland, OH 44195, USAM61 Cleveland Clinic, Bariatric and Metabolic Institute, 9500 Euclid Avenue, Cleveland, OH 44195, USAM61 Cleveland Clinic, Bariatric and Metabolic Institute, 9500 Euclid Avenue, Cleveland, OH 44195, USAM61 Cleveland Clinic, Bariatric and Metabolic Institute, 9500 Euclid Avenue, Cleveland, OH 44195, USABariatric/metabolic surgery is considered an accepted treatment option for type 2 diabetes mellitus (T2DM) with body mass index (BMI)  ≧  35 kg/m2. Mounting evidence also shows that metabolic surgery is effective for T2DM with BMI  <  35 kg/m2. To evaluate current status of metabolic surgery, we reviewed the available clinical studies which described surgical treatment for T2DM with mean BMI  <  35 kg/m2. 18 studies with 477 patients were identified. 30% of the patients was insulin users. The follow-up period ranged from 6 to 216 months. The weight loss effect was reasonable, not excessive. Mean BMI decreased from 30.4 to 24.8 kg/m2. Remission of T2DM was achieved in 64.7% of the patients with fasting plasma glucose and glycated hemoglobin approaching slightly above normal range. Clinical T2DM status was an important factor when selecting the eligible candidates for metabolic surgery. Postoperative complication rate of 10.3% with mortality of 0% in the studies has been acceptable. Even though it would be premature at this point to state that metabolic surgery is an accepted treatment option for T2DM with BMI < 35 kg/m2, it is clear that a high proportion of T2DM patients will derive substantial benefit from metabolic surgery.http://dx.doi.org/10.1155/2012/147256
spellingShingle Hideharu Shimizu
Poochong Timratana
Philip R. Schauer
Tomasz Rogula
Review of Metabolic Surgery for Type 2 Diabetes in Patients with a BMI < 35 kg/m2
Journal of Obesity
title Review of Metabolic Surgery for Type 2 Diabetes in Patients with a BMI < 35 kg/m2
title_full Review of Metabolic Surgery for Type 2 Diabetes in Patients with a BMI < 35 kg/m2
title_fullStr Review of Metabolic Surgery for Type 2 Diabetes in Patients with a BMI < 35 kg/m2
title_full_unstemmed Review of Metabolic Surgery for Type 2 Diabetes in Patients with a BMI < 35 kg/m2
title_short Review of Metabolic Surgery for Type 2 Diabetes in Patients with a BMI < 35 kg/m2
title_sort review of metabolic surgery for type 2 diabetes in patients with a bmi 35 kg m2
url http://dx.doi.org/10.1155/2012/147256
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