Associations between physical exercise patterns and pain symptoms in individuals with endometriosis: a cross-sectional mHealth-based investigation
Objectives This study investigates the association of daily physical exercise with pain symptoms in endometriosis. We also examined whether an individual’s typical weekly (ie, habitual) exercise frequency influences (ie, moderates) the relationship between their pain symptoms on a given day (day t)...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2022-07-01
|
| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/7/e059280.full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832575965653368832 |
|---|---|
| author | Ipek Ensari Suzanne Bakken Sharon Lipsky-Gorman Emma N Horan Noémie Elhadad |
| author_facet | Ipek Ensari Suzanne Bakken Sharon Lipsky-Gorman Emma N Horan Noémie Elhadad |
| author_sort | Ipek Ensari |
| collection | DOAJ |
| description | Objectives This study investigates the association of daily physical exercise with pain symptoms in endometriosis. We also examined whether an individual’s typical weekly (ie, habitual) exercise frequency influences (ie, moderates) the relationship between their pain symptoms on a given day (day t) and previous-day (day t-1) exercise.Participants The sample included 90 382 days of data from 1009 participants (~85% non-Hispanic white) living with endometriosis across 38 countries.Study design This was an observational, retrospective study conducted using data from a research mobile app (Phendo) designed for collecting self-reported data on symptoms and self-management of endometriosis.Primary outcome measures The two primary outcomes were the composite day-level pain score that includes pain intensity and location, and the change in this score from previous day (Δ-score). We applied generalised linear mixed-level models to examine the effect of previous-day exercise and habitual exercise frequency on these outcomes. We included an interaction term between the two predictors to assess the moderation effect, and adjusted for previous-day pain, menstrual status, education level and body mass index.Results The association of previous-day (day t-1) exercise with pain symptoms on day t was moderated by habitual exercise frequency, independent of covariates (rate ratio=0.96, 95% CI=0.95 to 0.98, p=0.0007 for day-level pain score, B=−0.14, 95% CI=−0.26 to −0.016, p=0.026 for Δ-score). Those who regularly engaged in exercise at least three times per week were more likely to experience favourable pain outcomes after having a bout of exercise on the previous day.Conclusions Regular exercise might influence the day-level (ie, short-term) association of pain symptoms with exercise. These findings can inform exercise recommendations for endometriosis pain management, especially for those who are at greater risk of lack of regular exercise due to acute exacerbation in their pain after exercise. |
| format | Article |
| id | doaj-art-a2ce131ee3d04a0a95728575fd5adc24 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-07-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-a2ce131ee3d04a0a95728575fd5adc242025-01-31T15:45:10ZengBMJ Publishing GroupBMJ Open2044-60552022-07-0112710.1136/bmjopen-2021-059280Associations between physical exercise patterns and pain symptoms in individuals with endometriosis: a cross-sectional mHealth-based investigationIpek Ensari0Suzanne Bakken1Sharon Lipsky-Gorman2Emma N Horan3Noémie Elhadad4Data Science Institute, Columbia University, New York, New York, USAData Science Institute, Columbia University, New York, New York, USADepartment of Biomedical Informatics, Columbia University, New York, New York, USADepartment of Biomedical Informatics, Columbia University, New York, New York, USAData Science Institute, Columbia University, New York, New York, USAObjectives This study investigates the association of daily physical exercise with pain symptoms in endometriosis. We also examined whether an individual’s typical weekly (ie, habitual) exercise frequency influences (ie, moderates) the relationship between their pain symptoms on a given day (day t) and previous-day (day t-1) exercise.Participants The sample included 90 382 days of data from 1009 participants (~85% non-Hispanic white) living with endometriosis across 38 countries.Study design This was an observational, retrospective study conducted using data from a research mobile app (Phendo) designed for collecting self-reported data on symptoms and self-management of endometriosis.Primary outcome measures The two primary outcomes were the composite day-level pain score that includes pain intensity and location, and the change in this score from previous day (Δ-score). We applied generalised linear mixed-level models to examine the effect of previous-day exercise and habitual exercise frequency on these outcomes. We included an interaction term between the two predictors to assess the moderation effect, and adjusted for previous-day pain, menstrual status, education level and body mass index.Results The association of previous-day (day t-1) exercise with pain symptoms on day t was moderated by habitual exercise frequency, independent of covariates (rate ratio=0.96, 95% CI=0.95 to 0.98, p=0.0007 for day-level pain score, B=−0.14, 95% CI=−0.26 to −0.016, p=0.026 for Δ-score). Those who regularly engaged in exercise at least three times per week were more likely to experience favourable pain outcomes after having a bout of exercise on the previous day.Conclusions Regular exercise might influence the day-level (ie, short-term) association of pain symptoms with exercise. These findings can inform exercise recommendations for endometriosis pain management, especially for those who are at greater risk of lack of regular exercise due to acute exacerbation in their pain after exercise.https://bmjopen.bmj.com/content/12/7/e059280.full |
| spellingShingle | Ipek Ensari Suzanne Bakken Sharon Lipsky-Gorman Emma N Horan Noémie Elhadad Associations between physical exercise patterns and pain symptoms in individuals with endometriosis: a cross-sectional mHealth-based investigation BMJ Open |
| title | Associations between physical exercise patterns and pain symptoms in individuals with endometriosis: a cross-sectional mHealth-based investigation |
| title_full | Associations between physical exercise patterns and pain symptoms in individuals with endometriosis: a cross-sectional mHealth-based investigation |
| title_fullStr | Associations between physical exercise patterns and pain symptoms in individuals with endometriosis: a cross-sectional mHealth-based investigation |
| title_full_unstemmed | Associations between physical exercise patterns and pain symptoms in individuals with endometriosis: a cross-sectional mHealth-based investigation |
| title_short | Associations between physical exercise patterns and pain symptoms in individuals with endometriosis: a cross-sectional mHealth-based investigation |
| title_sort | associations between physical exercise patterns and pain symptoms in individuals with endometriosis a cross sectional mhealth based investigation |
| url | https://bmjopen.bmj.com/content/12/7/e059280.full |
| work_keys_str_mv | AT ipekensari associationsbetweenphysicalexercisepatternsandpainsymptomsinindividualswithendometriosisacrosssectionalmhealthbasedinvestigation AT suzannebakken associationsbetweenphysicalexercisepatternsandpainsymptomsinindividualswithendometriosisacrosssectionalmhealthbasedinvestigation AT sharonlipskygorman associationsbetweenphysicalexercisepatternsandpainsymptomsinindividualswithendometriosisacrosssectionalmhealthbasedinvestigation AT emmanhoran associationsbetweenphysicalexercisepatternsandpainsymptomsinindividualswithendometriosisacrosssectionalmhealthbasedinvestigation AT noemieelhadad associationsbetweenphysicalexercisepatternsandpainsymptomsinindividualswithendometriosisacrosssectionalmhealthbasedinvestigation |