Heterogeneity and breadth of host antibody response to KSHV infection demonstrated by systematic analysis of the KSHV proteome.

Heterogeneity and breadth of host antibody response to KSHV infection demonstrated by systematic analysis of the KSHV proteome.

The Kaposi sarcoma associated herpesvirus (KSHV) genome encodes more than 85 open reading frames (ORFs). Serological evaluation of KSHV infection now generally relies on reactivity to just one latent and/or one lytic protein (commonly ORF73 and K8.1). Most of the other polypeptides encoded by the vi...

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Main Authors: Nazzarena Labo, Wendell Miley, Vickie Marshall, William Gillette, Dominic Esposito, Matthew Bess, Alexandra Turano, Thomas Uldrick, Mark N Polizzotto, Kathleen M Wyvill, Rachel Bagni, Robert Yarchoan, Denise Whitby
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004046&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004046&type=printable

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