Characterization of the adaptive immune response in a mouse model for HPV-positive head and neck squamous cell carcinoma with implications to human disease

Characterization of the adaptive immune response in a mouse model for HPV-positive head and neck squamous cell carcinoma with implications to human disease

Abstract Head and neck squamous cell carcinoma (HNSCC) is the seventh most common cancer worldwide with a poor prognosis for survival. Risk factors include alcohol and tobacco abuse and infection with human papilloma virus (HPV). To enhance anti-tumor immune responses immunotherapeutic approaches ar...

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Bibliographic Details
Main Authors: Franziska Oliveri, Linda Neher, Ronja Pscheid, Isabel Sewald, Sowmya Gowdavally, Annika C. Betzler, Jaqueline Hallitsch, Jens Greve, Simon Laban, Sebastian Schmid, Thomas K. Hoffmann, Patrick J. Schuler, Cornelia Brunner
Format: Article
Language:English
Published: Springer 2025-01-01
Series:Cancer Immunology, Immunotherapy
Subjects:
Head and neck cancer
HPV
Immune checkpoints
Tumor-infiltrating lymphocytes
Online Access:https://doi.org/10.1007/s00262-024-03907-y
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