Development of nucleus-targeted histone-tail-based photoaffinity probes to profile the epigenetic interactome in native cells

Abstract Dissection of the physiological interactomes of histone post-translational modifications (hPTMs) is crucial for understanding epigenetic regulatory pathways. Peptide- or protein-based histone photoaffinity tools expanded the ability to probe the epigenetic interactome, but in situ profiling...

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Bibliographic Details
Main Authors: Yu Wang, Jian Fan, Xianbin Meng, Qingyao Shu, Yincui Wu, Guo-Chao Chu, Rong Ji, Yinshan Ye, Xiangwei Wu, Jing Shi, Haiteng Deng, Lei Liu, Yi-Ming Li
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55046-8
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