A phase 2 study of decitabine with or without carboplatin and arsenic trioxide in patients with MDS and AML

Abstract: Although decitabine (DAC) shows activity against myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), patient responses are limited, and prognoses remain poor. Preclinical studies have indicated that arsenic trioxide (ATO) and carboplatin (Carbo) enhance DAC’s epigenetic gene d...

Full description

Saved in:
Bibliographic Details
Main Authors: Patricia L. Kropf, Woonbok Chung, Raji Shameem, Lianchun Xiao, Curt Balch, Xuelin Huang, Jean-Pierre J. Issa
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Blood Neoplasia
Online Access:http://www.sciencedirect.com/science/article/pii/S2950328025000068
Tags: Add Tag
No Tags, Be the first to tag this record!