FHL2 activates β-catenin/Wnt signaling by complexing with APC and TRIM63 in lung adenocarcinoma

FHL2 activates β-catenin/Wnt signaling by complexing with APC and TRIM63 in lung adenocarcinoma

Objectives: Four and a half LIM domain 2 protein (FHL2) was reported to regulate the progression of various cancers and this study aimed to clarify the intrinsic mechanism of FHL2 facilitating the progression of lung adenocarcinoma. Methods: In this study, bioinformatic analysis and immunohistochemi...

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Bibliographic Details
Main Authors: Jian Gao, Yong-Qiang Ao, Jie Deng, Miao Lin, Shuai Wang, Jia-Hao Jiang, Jian-Yong Ding
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Translational Oncology
Subjects:
FHL2
APC
TRIM63
β-catenin
LUAD
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324002584
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