Construction of stable packaging cell lines for large-scale industrial BaEV-enveloped retroviral vector production

Construction of stable packaging cell lines for large-scale industrial BaEV-enveloped retroviral vector production

IntroductionViral vectors with Baboon endogenous virus (BaEV) envelope proteins have been demonstrated to markedly increase gene transfer efficiency to NK cells. Nevertheless, the cytotoxicity of the BaEV envelope protein necessitates the production of this type of viral vector by transient transfec...

Full description

Saved in:
Bibliographic Details
Main Authors: Lijun Zhao, Chunting Qiu, Hanyi Chen, Zhuoying Yu, Jiaqi Fan, Qihong Ma, Sijian Zhan, Yaru Feng, Xiaorui Li, Ping Ma, Weijia Wang, Yuanyuan Shi, Jin-fu Xu, Jianxun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
BaEV-enveloped retrovirus
stable packaging cell line
industrial-large-scale production
CAR-NK cell therapy
ASCT-1/2 knockout
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1578660/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2025.1578660/full

Similar Items