The gut microbiome and metabolomic alterations underlying colitis-induced encephalopathy in mice: mechanistic insight

The gut microbiome and metabolomic alterations underlying colitis-induced encephalopathy in mice: mechanistic insight

Abstract Background In addition to classical gastrointestinal symptoms, patients with inflammatory bowel disease (IBD) often exhibit neurological manifestations, such as mood disorders and cognitive dysfunctions, which are frequently overlooked. However, the potential pathogenesis of IBD-related enc...

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Main Authors: Aimin Cai, Dingchao Shen, Qiushuang Xiong, Shize Li, Chenyu Qiu, Lele Li, Zhiwei Chen, Xinlu Lin, Qing Yao, Youting Zhang, Ruijie Chen, Longfa Kou
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Behavioral and Brain Functions
Subjects:
DSS-induced colitis
Metabolism
Microbiota-gut-brain axis
Mood disorders
Cognitive dysfunctions
Online Access:https://doi.org/10.1186/s12993-025-00283-0
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https://doi.org/10.1186/s12993-025-00283-0

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