Synthetic approaches to 2-aryl/hetaryl- and 2-(hetaryl)ylidene derivatives of fluorinated 1,3-benzothiazin-4-ones

Synthetic approaches to 2-aryl/hetaryl- and 2-(hetaryl)ylidene derivatives of fluorinated 1,3-benzothiazin-4-ones

A series of 2-hetaryl- and 2-(hetaryl)ylidene substituted 5-fluoro-8-nitro-1,3-benzothiazin-4-ones was synthesized by interaction of 2,6-difluoro-3-nitrobenzoylisothiocyanate with C-nucleophiles. Cyclocondensation of polyfluorobenzoylchlorides with aryl and hetaryl thioamides represents new approach...

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Bibliographic Details
Main Authors: Emiliya V. Nosova, Olga A. Batanova, Nataliya N. Mochulskaya, Galina N. Lipunova
Format: Article
Language:English
Published: Ural Federal University 2020-09-01
Series:Chimica Techno Acta
Subjects:
1,3-benzothiazin-4-ones
2-fluorobenzoylchloride
2-fluorobenzoyl-isothiocyanate
indole
pyrrole
cyanomethylbenzimidazole
benzoylmethylbenzimidazole
thioamide
cyclocondensation
tuberculostatics
Online Access:https://chimicatechnoacta.ru/article/view/4537
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