Selecting Negative Samples for PPI Prediction Using Hierarchical Clustering Methodology

Protein-protein interactions (PPIs) play a crucial role in cellular processes. In the present work, a new approach is proposed to construct a PPI predictor training a support vector machine model through a mutual information filter-wrapper parallel feature selection algorithm and an iterative and hi...

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Bibliographic Details
Main Authors: J. M. Urquiza, I. Rojas, H. Pomares, J. Herrera, J. P. Florido, O. Valenzuela
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Applied Mathematics
Online Access:http://dx.doi.org/10.1155/2012/897289
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