Prevalence of diabetes-related sarcopenia and its defining components within primary care: A cross-sectional study
Background: Diabetes-related sarcopenia is a significant contributor to the global prevalence of sarcopenia. Both conditions become more prevalent with age and amplify the risk of adverse outcomes. This study aimed to assess the prevalence of sarcopenia and at-risk morphofunctional (MF) phenotypes a...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-04-01
|
| Series: | Diabetes Epidemiology and Management |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666970625000010 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832573026158247936 |
|---|---|
| author | Rubén Silva-Tinoco Lilia Castillo-Martínez Berenice Cabrera-Victoria Eileen Guzmán-Olvera Christian Hinojosa-Segura Alejandro Avalos-Bracho Cira Santillán-Díaz |
| author_facet | Rubén Silva-Tinoco Lilia Castillo-Martínez Berenice Cabrera-Victoria Eileen Guzmán-Olvera Christian Hinojosa-Segura Alejandro Avalos-Bracho Cira Santillán-Díaz |
| author_sort | Rubén Silva-Tinoco |
| collection | DOAJ |
| description | Background: Diabetes-related sarcopenia is a significant contributor to the global prevalence of sarcopenia. Both conditions become more prevalent with age and amplify the risk of adverse outcomes. This study aimed to assess the prevalence of sarcopenia and at-risk morphofunctional (MF) phenotypes and to identify the factors associated in patients with type 2 diabetes (T2D), including non-elderly adults, in primary care settings Methods: This cross-sectional study included 261 individuals managed in primary care units in Mexico City, between July 2022 and May 2024. Assessments followed the guidelines of the European Working Group on Sarcopenia in Older Adults (EWGSOP2) to identify isolated low muscle mass, low muscle strength, and sarcopenia or severe sarcopenia Results: The mean age of the participants (57.1 % female) was 51.1 ± 12.1 years, with a median diabetes duration of 7 (1–15) years. An altered MF assessment was observed in 159 participants, with 14.1 % exhibiting sarcopenia, 5.4 % isolated low muscle strength, and 41.4 % isolated low muscle mass. Univariate logistic regression analysis identified that age, educational level, diabetes duration, weight, body mass index, waist circumference, hip circumference, fat mass, use, and insulin dose were associated with altered MF assessment. Multivariable analyses showed that hip circumference and hypertriglyceridemia were associated with a lower risk of altered MF assessment, whereas the interactions between age and fat mass increased the risk. Conclusions: This primary care study, which included elderly and non-elderly adults with T2D, revealed a relatively high prevalence of altered MF assessments, including sarcopenia, low muscle strength, and low muscle mass. Early recognition of sarcopenia spectrum disorders is essential for the timely prevention of adverse outcomes related to diabetic sarcopenia in primary care settings. |
| format | Article |
| id | doaj-art-a193357e19334b65888edbed62d7a1a6 |
| institution | Kabale University |
| issn | 2666-9706 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Diabetes Epidemiology and Management |
| spelling | doaj-art-a193357e19334b65888edbed62d7a1a62025-02-02T05:29:28ZengElsevierDiabetes Epidemiology and Management2666-97062025-04-0118100252Prevalence of diabetes-related sarcopenia and its defining components within primary care: A cross-sectional studyRubén Silva-Tinoco0Lilia Castillo-Martínez1Berenice Cabrera-Victoria2Eileen Guzmán-Olvera3Christian Hinojosa-Segura4Alejandro Avalos-Bracho5Cira Santillán-Díaz6Clínica Especializada en el Manejo de la Diabetes en la Ciudad de México, Servicios Públicos de Salud del Instituto Mexicano del Seguro Social para el Bienestar, Mexico; Unidad de Atención a la Salud, Instituto Mexicano del Seguro Social para el Bienestar, MexicoServicio de Nutriología Clínica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, MexicoClínica Especializada en el Manejo de la Diabetes en la Ciudad de México, Servicios Públicos de Salud del Instituto Mexicano del Seguro Social para el Bienestar, MexicoClínica Especializada en el Manejo de la Diabetes en la Ciudad de México, Servicios Públicos de Salud del Instituto Mexicano del Seguro Social para el Bienestar, MexicoClínica Especializada en el Manejo de la Diabetes en la Ciudad de México, Servicios Públicos de Salud del Instituto Mexicano del Seguro Social para el Bienestar, MexicoUnidad de Atención a la Salud, Instituto Mexicano del Seguro Social para el Bienestar, MexicoPrograma Universitario de Investigación sobre Riesgos Epidemiológicos y Emergentes, Universidad Nacional Autónoma de México, Mexico; Corresponding author.Background: Diabetes-related sarcopenia is a significant contributor to the global prevalence of sarcopenia. Both conditions become more prevalent with age and amplify the risk of adverse outcomes. This study aimed to assess the prevalence of sarcopenia and at-risk morphofunctional (MF) phenotypes and to identify the factors associated in patients with type 2 diabetes (T2D), including non-elderly adults, in primary care settings Methods: This cross-sectional study included 261 individuals managed in primary care units in Mexico City, between July 2022 and May 2024. Assessments followed the guidelines of the European Working Group on Sarcopenia in Older Adults (EWGSOP2) to identify isolated low muscle mass, low muscle strength, and sarcopenia or severe sarcopenia Results: The mean age of the participants (57.1 % female) was 51.1 ± 12.1 years, with a median diabetes duration of 7 (1–15) years. An altered MF assessment was observed in 159 participants, with 14.1 % exhibiting sarcopenia, 5.4 % isolated low muscle strength, and 41.4 % isolated low muscle mass. Univariate logistic regression analysis identified that age, educational level, diabetes duration, weight, body mass index, waist circumference, hip circumference, fat mass, use, and insulin dose were associated with altered MF assessment. Multivariable analyses showed that hip circumference and hypertriglyceridemia were associated with a lower risk of altered MF assessment, whereas the interactions between age and fat mass increased the risk. Conclusions: This primary care study, which included elderly and non-elderly adults with T2D, revealed a relatively high prevalence of altered MF assessments, including sarcopenia, low muscle strength, and low muscle mass. Early recognition of sarcopenia spectrum disorders is essential for the timely prevention of adverse outcomes related to diabetic sarcopenia in primary care settings.http://www.sciencedirect.com/science/article/pii/S2666970625000010SarcopeniaDiabetes mellitus type 2Primary health carePrevalenceAgeingBody composition |
| spellingShingle | Rubén Silva-Tinoco Lilia Castillo-Martínez Berenice Cabrera-Victoria Eileen Guzmán-Olvera Christian Hinojosa-Segura Alejandro Avalos-Bracho Cira Santillán-Díaz Prevalence of diabetes-related sarcopenia and its defining components within primary care: A cross-sectional study Diabetes Epidemiology and Management Sarcopenia Diabetes mellitus type 2 Primary health care Prevalence Ageing Body composition |
| title | Prevalence of diabetes-related sarcopenia and its defining components within primary care: A cross-sectional study |
| title_full | Prevalence of diabetes-related sarcopenia and its defining components within primary care: A cross-sectional study |
| title_fullStr | Prevalence of diabetes-related sarcopenia and its defining components within primary care: A cross-sectional study |
| title_full_unstemmed | Prevalence of diabetes-related sarcopenia and its defining components within primary care: A cross-sectional study |
| title_short | Prevalence of diabetes-related sarcopenia and its defining components within primary care: A cross-sectional study |
| title_sort | prevalence of diabetes related sarcopenia and its defining components within primary care a cross sectional study |
| topic | Sarcopenia Diabetes mellitus type 2 Primary health care Prevalence Ageing Body composition |
| url | http://www.sciencedirect.com/science/article/pii/S2666970625000010 |
| work_keys_str_mv | AT rubensilvatinoco prevalenceofdiabetesrelatedsarcopeniaanditsdefiningcomponentswithinprimarycareacrosssectionalstudy AT liliacastillomartinez prevalenceofdiabetesrelatedsarcopeniaanditsdefiningcomponentswithinprimarycareacrosssectionalstudy AT berenicecabreravictoria prevalenceofdiabetesrelatedsarcopeniaanditsdefiningcomponentswithinprimarycareacrosssectionalstudy AT eileenguzmanolvera prevalenceofdiabetesrelatedsarcopeniaanditsdefiningcomponentswithinprimarycareacrosssectionalstudy AT christianhinojosasegura prevalenceofdiabetesrelatedsarcopeniaanditsdefiningcomponentswithinprimarycareacrosssectionalstudy AT alejandroavalosbracho prevalenceofdiabetesrelatedsarcopeniaanditsdefiningcomponentswithinprimarycareacrosssectionalstudy AT cirasantillandiaz prevalenceofdiabetesrelatedsarcopeniaanditsdefiningcomponentswithinprimarycareacrosssectionalstudy |