CCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunction.

<h4>Background</h4>The linkages between neuroinflammation and Alzheimer's disease (AD) pathogenesis are well established. What is not, however, is how specific immune pathways and proteins affect the disease. To this end, we previously demonstrated that transgenic over-expression of...

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Bibliographic Details
Main Authors: Tomomi Kiyota, Masaru Yamamoto, Huangui Xiong, Mary P Lambert, William L Klein, Howard E Gendelman, Richard M Ransohoff, Tsuneya Ikezu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0006197&type=printable
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