Role of Maternal Obesity in Offspring Cardiovascular Development and Congenital Heart Defects

Role of Maternal Obesity in Offspring Cardiovascular Development and Congenital Heart Defects

Background Congenital heart disease is a leading cause of death in newborns, yet many of its molecular mechanisms remain unknown. Both maternal obesity and diabetes increase the risk of congenital heart disease in offspring, with recent studies suggesting these conditions may have distinct teratogen...

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Bibliographic Details
Main Authors: Ashleigh McMullan, James B. Zwierzynski, Nina Jain, Laura S. Haneline, Weinian Shou, Kok Lim Kua, Swetansu K. Hota, Matthew D. Durbin
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiac development
congenital heart disease
gene–environment interaction
maternal obesity
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.039684
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