TMAO metaorganismal pathway and chronic inflammatory diseases
Nutrients containing a trimethylamine (TMA) moiety in their structure can be metabolized by the gut microbiota through enzymatic cleavage of the C-N bond, producing TMA. In the liver, TMA is subsequently oxidized to trimethylamine N-oxide (TMAO) by flavin monooxygenases (FMOs). TMAO exerts pro-ather...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Open Exploration Publishing Inc.
2025-06-01
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| Series: | Exploration of Medicine |
| Subjects: | |
| Online Access: | https://www.explorationpub.com/uploads/Article/A1001339/1001339.pdf |
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